Deion Sanders may be dealing with blood clots again. Sanders coached much of Colorado's 35-21 loss to TCU without a shoe on his left foot. After the game he said it was because his foot was in so much pain. [Yahoo Sports TV is here! Watch live shows and highlights 24/7] "I think I got more blood clots," Sanders said after the game. "Cat's out of the bag, all right. I think I got more blood clots. It don't make sense. I'm hurting like crazy. I got a doctor's appointment on Monday to see what time it is. So that's what's going on. I'm not getting blood to my leg, that's why my leg is throbbing. "I'm sorry to get that out, but thank you for noticing." Sanders dealt with blood clots in the fall of 2021 while he was coaching Jackson State. He had surgery on his left foot, and the school's trainer noticed toes on his foot had turned black. Sanders ended up having the two biggest toes on his left foot amputated because of the femoral arterial clots. In the summer of 2023, Sanders missed Pac-12 media day due to surgery for blood clots in his right leg. This summer,Sanders announced he had his bladder removedafter he was diagnosed with bladder cancer. Sanders said he elected to have his bladder completely removed because of the cancer's recurrence rate. Colorado assistant trainer Lauren Askevold — the same person who noticed Sanders' toes at Jackson State — said Sanders' bladder cancer was discovered as doctors went over the vascular tests he undergoes because of the blood clot issues. Saturday night, Colorado turned the ball over four times for the first time since 2022 in the loss. TCU tied the game at 14-14 before halftime after a Kaidon Salter interception and intercepted Salter again at the goal line right at the end of the second quarter as Colorado was threatening to take a 21-14 lead. The Colorado QB finished with three interceptions and was 18-of-29 passing for 217 yards and two touchdowns. The loss dropped the Buffs to 3-3 overall and 1-2 in the Big 12. "It's frustrating because I'm seeing what you see. I felt like — and this is no disrespect to TCU because they're well-coached, they did a wonderful job, quarterback made plays — I feel like we're the better team," Sanders said. "I felt like that last week and the week before. But yet and still we're in this situation."